"Who said there are no assurances in life? I assure you this is going to hurt."

Incinerate

Incinerate deals 3 damage to any target. A creature dealt damage this way can't be regenerated this turn.

"Never taunt an embermage, 'What are you going to do about it?'"
—Akin, seasoned askari

The List

Duel Decks Anthology: Jace vs. Chandra

Incinerate deals 3 damage to target creature or player. A creature dealt damage this way can't be regenerated this turn.

Magic Online Promos

"Spontaneous combustion is a myth. If you burst into flame, someone wanted you to."
—Chandra Nalaar

Magic 2012

Salvat 2011

Regeneration abilities that would affect that creature can still be activated; they just won’t do anything. The creature can’t be regenerated for any reason, even if an effect other than Incinerate would deal lethal damage to it or otherwise destroy it.